movements of chemical mediators to the injured area
Systemic Effect
An infectious microorganisms can escape the confines of the immediate tissue via the circulatory system where it may spread to other parts of the body.
Systemic effect happens when inflammation overwhelms the host. When it is due to infection the term sepsis is applied.
Systemic inflammation and obesity
With the discovery of interleukins the concepts of systemic inflammation developed. Systemic inflammation is not confined to a particular tissue but involved the endothelium and other organ system.
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